geoffrey g. murphy, phd
Associate Professor, Molecular & Integrative Physiology
Associate Research Professor, Molecular and Behavioral Neuroscience Institute
Dr. Murphy currently holds a dual appointment at the University of Michigan Medical School. He holds a tenured Instructional track appointment in the Department of Molecular and Integrative Physiology and a Research track appointment in the Molecular & Behavioral Neuroscience Institute.
His group makes and uses genetically engineered mice and a multidisciplinary approach that combines aspects of modern molecular biology, behavioral neuroscience and in vitro electrophysiology. This approach has allowed the group to address questions at the basic neuroscience level as well as questions that are more translational in nature. Their work has been funded by the National Institute on Aging (NIA), the National Institute of Neurological Disorders & Stroke (NINDS), the Department of Defense as well as private foundations
Dr. Murphy’s group has extensive experience using in vitro brain slices acutely prepared from mice, rats and human subjects. They routinely make in vitro recordings using a wide range of methodologies including extracellular field potentials, whole-cell patch (current and voltage clamp) and sharp electrodes. Similarly, they have published numerous peer-reviewed papers using mice as a model system to study normal cognitive function as well as disease related cognitive impairments.