Therapeutic Vibration Device

We’ve built and tested a full-body device that helps ICU patients avoid Post Intensive Care Syndrome (PICS) by applying vibration to activate their muscles. The device has four entry points, two at the shoulders and two at the feet. Not only does the system apply vibrations at both ends of the skeletal system, it also compresses the body and tightens the joints so the vibrations travel all the way through the body.

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Desktop Digital Biomarker Analysis System

We’ve built a rapid, accurate, and highly multiplexed digital immunoassay device. Measuring a large panel of protein biomarkers near the bedside has the potential to transform patient critical care. By incorporating machine learning-based autonomous image analysis, the assay chip and instrument have achieved 12-plexed pro-inflammatory biomarker detection at concentrations of < 10pg/mL with a sample volume of < 10 μL, including all processes from sampling to data analysis within 30 minutes, while only requiring a 5-minute assay incubation.

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Digital External Ventricular Drain (DEVD) with Data Analytics Integration

The DEVD will provide caregivers from the field hospital to the ICU the ability to automatically quantify, regulate, and monitor ICP and cerebrospinal fluid (CSF) drainage. The DEVD has the potential to move an industry away from the old rope and pulley system into the modern era. Ready for wireless and analytic integration, the DEVD can also be used to stream data that can be utilized in predictive modeling for advanced TBI diagnosis and treatment.

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Point-of-Care Microfluidic Platform for Detecting Traumatic Brain Injury (TBI)

This is a hand-held device that sends blood test results of traumatic brain injury (TBI) patients directly to a smartphone while utilizing a series of blood-based biomarkers that can be used to monitor individual patient response to TBI treatment regardless of their state. This point-of-care platform is suited for performing repeated measurements at a fraction of current hospital costs.

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Portable Disease and Pathogen Detection System

This innovative, handheld POC biomarker immunosensor system is a battery-operated, highly portable, pipette-shaped biomarker analysis microsystem that is wirelessly connected to a smartphone for data transmission and analysis. Because current critical care practice is insufficient to monitor the dynamic nature of sepsis, this device stands ready to improve outcomes and save lives.

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Environment for Model Maintenance, Integration and Tuning (EMMIT)

EMMIT solves a critical problem for predictive analytics in a hospital setting. By providing a hosting solution outside of EHR systems, EMMIT can monitor the flow of data between systems and notify teams of errors or downtime. EMMIT’s usefulness scales with the ability to host and monitor the operation of multiple models simultaneously.

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Redox Point-of-Care Platform

The Redox Point-of-Care platform is the first to allow measurement of redox in whole blood and other fluids in the clinical setting, rapidly, in real-time - and it does it at bedside, where it is needed most to affect change. It contains sensor technology that utilizes nanoporous gold electrodes integrated into a microfluidic device to directly measure oxidation reduction (redox) in whole blood at 250 microliter sample amounts without the risk of contamination or biofouling.

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