shuichi takayama, phd
Professor & Associate Chair, Technology Transfer, Biomedical Engineering
Professor, Macromolecular Science and Engineering Program
Investigator, Biointerfaces Institute
Dr. Takayama is Professor and Associate Chair for Technology Transfer in the Department of Biomedical Engineering at the University of Michigan. He also has an appointment in the Macromolecular Science and Engineering Program and currently serves on the executive committee of the Biointerfaces Institute, a multidisciplinary program between the School of Medicine and Dentistry and the Colleges of Pharmacy and Engineering at UM. He received his PhD from the Scripps Research Institute in 1998 and was a Leukemia and Lymphoma Society Postdoctoral Fellow at Harvard University from 1998-2000. He joined the University of Michigan in fall 2000.
His current technological research interests include microfluidics, nanofluidics, aqueous two phase systems, fracture fabrication, and microscale tissue engineering. The technologies are used to construct in vitro cell and tissue culture systems the recreate human physiology as well as to perform biochemical analyses. Examples of microfluidic models of the body constructed include micro-engineered models of lung injury, artificial oviducts for enhanced in vitro fertilization treatment, and 3D models of cancer metastasis. Examples of bioanalysis applications include crosstalk free multiplexed immunoassays for diagnosis of graft-versus-host-disease, multi-color histone modification mapping from single chromatin strands using nanofluidics, and dissecting G-protein coupled receptor signaling pathways through biochemical phase locking analysis. Dr. Takayama’s work has been funded by the NIH (NCI, NIGMS, NHGRI, NHLBI, NIBIB, NICHD), NSF (BES, DMI, CMMI, DBI, IIP), DTRA, Army, and others.
Dr. Takayama serves on the editorial board of the journals Microfluidics and Nanofluidics and Journal of Mechanics in Medicine and Biology and reviews for numerous journals in the micro/nanotechnology, materials science, physical sciences, and biology. He has published over 150 peer-reviewed articles. He is a standing member of the Instrumentation and Systems Development (ISD) Study Section at the Center for Scientific Review within the NIH and routinely assists with grant reviews in the area of instrumentation development. Dr. Takayama is also prolific inventor and has been recognized as the advisor of a Collegiate Inventor’s Award in Microfluidics from the National Inventors Hall of Fame & US Patent and Trademark Office. Other honors include The Ralph E. Powe Junior Faculty Award, NSF Career Award, College of Eng, George J Huebner, Jr Research Excellence Award, and 3Rs Highly Commended Award.