james morrissey, phd


Professor, Biological Chemistry
Professor, Cardiovascular, Internal Medicine



Jim Morrissey received his Ph.D. from the University of California at San Diego and did postdoctoral research at the University of Oxford and the Scripps Research Foundation. Since the mid-1980s, Dr. Morrissey's research focuses on biochemical mechanisms by which the blood clotting system is triggered, with a particular emphasis on studying protein-membrane interactions in clotting. In 2006, his laboratory also discovered that inorganic polyphosphate, which is released from activated human platelets, is a potent modulator of blood clotting and inflammation. Work from his lab has led to a number of spin-offs with potential clinical applications, including new diagnostic assays. His lab is also working on novel hemostatic agents for treating bleeding, and anti-inflammatory/anti-thrombotic agents with potential for reduced bleeding side effects relative to conventional anticoagulant drugs