Dr. Hasan B. Alam is the Norman Thompson Professor of Surgery and Section Head for the Section of General Surgery at the University of Michigan Hospital. He is an Acute Care Surgeon who is certified by the American Board of Surgery in General Surgery and Surgical Critical Care. He received his surgical training at the Washington Hospital Center in Washington DC, followed by a post-doctoral research fellowship at the Uniformed Services University of Health Sciences (USUHS) in Bethesda, MD. He then served as a faculty member at the Georgetown University as well as USUHS before moving to Boston to join the Massachusetts General Hospital (MGH) in 2005. There he was rapidly promoted to the position of Professor of Surgery at the Harvard Medical School, and served as the Director of Surgical Critical Care Fellowship Program at the MGH. He was also the founding Medical Director of the multi-disciplinary Intensive Care Unit, and chaired the State Committee on Trauma for many years before moving to Ann Arbor in 2012. Dr. Alam’s clinical interests are in the areas of trauma, emergency general surgery and surgical critical care. His research focuses on hemorrhagic shock, traumatic brain injuries, resuscitation techniques, novel cell preservation strategies, modulation of response to lethal insults, therapeutic hypothermia, hemorrhage control, and development of new treatments for sepsis. This research is funded by large federal grants by the National Institutes of Health as well as by the US Department of Defense. He has published nearly 200 manuscripts and book chapters and is the holder of 6 patents. He has won numerous awards for excellence in teaching and research, and serves on the editorial boards of nearly all of the leading surgical, trauma and critical care journals. He is a member of more than 15 surgical/scientific societies including the American Surgical Association, American Association for the Surgery of Trauma, Society of University Surgeons, and the Society of Clinical Surgery.
Anne Cain-Nielsen, MS, previously worked as a staff researcher at the University of Minnesota’s HIV/STI Intervention and Prevention Studies Program and completed an internship at the Mayo Clinic’s Division of Health Care Policy and Research.
Ms. Cain-Nielsen received a BA in Economics from the University of Minnesota and an MS in Biostatistics from the University of Michigan. At the University of Michigan, she performs data analysis for the Michigan Trauma Quality Improvement Program (MTQIP), Michigan Bariatric Surgery Collaborative (MBSC), and Center for Healthcare Outcomes and Policy (CHOP) projects focusing on quality and costs of surgical and medical care.
Jill R. Cherry-Bukowiec, M.D., M.S. is a Clinical Assistant Professor in the Section of General Surgery at the University of Michigan in Ann Arbor. She provides clinical coverage in trauma, non-trauma emergency, general surgery and surgical critical care.
Dr. Cherry received her BA in Zoology from Miami University in Oxford, Ohio. She graduated from the Medical College of Ohio at the University of Toledo and completed General Surgery residency at the Eastern Virginia Medical School. She received her Master of Science degree in Clinical Research Design and Statistical Analysis from the University of Michigan. She is board certified in General Surgery, Surgical Critical Care, and by the National Board of Physician Nutrition Specialists. She is also a Fellow of the American College of Surgeons.
Dr. Cherry's clinical interests focus on Surgical Critical Care, Trauma, Non-Trauma Emergency and General Surgery. She is the Medical Director of the University of Michigan Trauma Burn ICU and provides surgical care for injured patients and patients with acute general surgery problems. She has a special interest in patients with severe infection and sepsis, and challenging nutrition. She also serves the health system as a voting member for the Executive Council of Clinical Affairs (ECCA).
Dr. Cherry has a strong interest in clinical nutrition. She was a recipient of the Nestle Nutrition Institute Enteral Nutrition Fellowship. She serves on the National Board for Nutrition Physician Specialists representing the Society of Critical Care Medicine (SCCM). She is a Past-President of the Michigan Society for Parenteral and Enteral Nutrition and currently serves on the society’s physician director. She is the founder of the Nutrition Advisory Committee for the University of Michigan Hospital and currently acts as physician advisor for the committee.
Dr. Cherry also has a strong interest in teaching medical students and residents. She is the Assistant Scientific Trunk Director for the Medical School, Doctoring Faculty for the Medical School Doctoring Course, and Faculty for the Chief Concerns Medical Student Course. She is also the Faculty Lead for the new University of Michigan medical student curriculum M1 Nutrition Course, and is heavily involved in Surgical Resident Education as acts as the Acute Care Surgery Education Coordinator.
Dr. Cherry's clinical research is focused on critical care of the surgical patient with particular focus in nutrition and infection. Her education research focuses on medical student education.
Patrick Georgoff is a General Surgery resident, Surgical Critical Care fellow, and research fellow in the Trauma Surgery Research Laboratory at the University of Michigan. He obtained a B.S. in Movement Science from the University of Michigan before spending time as a research fellow at the National Institutes of Health (NIAID). He then went on to earn a M.D. from the Perelman School of Medicine at the University of Pennsylvania before returning to Ann Arbor to complete his surgical and critical care training.
Dr. Georgoff's clinical interest include critical care of the injured patient, hemorrhagic shock, and traumatic brain injury (TBI). Under the guidance of Dr. Hasan Alam, Dr. Georgoff's research focuses on novel resuscitation techniques, early treatment of (TBI), and the use of advanced genomic and proteomic technology to identify new treatment strategies for injured patients.
Dr. Hemmila is an Associate Professor of Surgery in the Division of Acute Care Surgery at the University of Michigan. He also serves on the Medical Liability Review Committee and is a national member of the American College of Surgeons Committee on Trauma. Dr. Hemmila received his B.S. in Chemical Engineering from the University of Rochester-Rochester, NY in 1985. Postgraduate study in Chemical Engineering and Biomedical Engineering was performed at Columbia University-NYC, NY. Dr. Hemmila graduated from the University of Michigan Medical School in 1994 and from General Surgery residency at the University of Michigan Medical Center in 2001. During his residency, he completed a Critical Care fellowship and conducted laboratory research on Extracorporeal Life Support. He is board certified in the specialties of Surgery and Surgical Critical Care.
Mark Hemmila's clinical interests are focused on providing surgical care for trauma or burn injured patients and patients with acute general surgery problems. His elective practice includes, but is not limited to, treatment of benign or neoplastic disease of the GI tract, hernia surgery, spine exposure, and laparoscopic procedures. He also provides critical care services for patients in the trauma and burn ICU with an interest in patients with severe respiratory failure. Dr. Hemmila’s laboratory research focus includes burn and wound inflammation, utilization of local topical burn wound therapy to attenuate inflammation following thermal injury, and pathophysiology/treatment of bacterial pneumonia. He has received extramural funding from the NIH, Department of Defense, the American College of Surgeons, and the American Association for the Surgery of Trauma.
Since 2006, Dr. Hemmila has been involved in creation and conduct of the American College of Surgeons Trauma Quality Improvement Program (ACS-TQIP). He serves as an advisor to TQIP and the National Trauma Data Bank. Based upon the success of previous Blue Cross Blue Shield of Michigan (BCBSM) funded clinical registry and collaborative quality improvement programs, Dr. Hemmila launched the Michigan Trauma Quality Improvement Program (MTQIP). The initial program was funded by BCBSM Foundation as a pilot project from 2008 to 2010. BCBSM formalized this CQI in January of 2011. Mark Hemmila serves as the program director of MTQIP which brings together 23 participating trauma centers in Michigan to focus on quality improvement at a statewide level. As a member of the Center for Healthcare Outcomes and Policy (CHOP) at the University of Michigan, Dr. Hemmila concentrates on optimizing patient outcomes in the area of Acute Care Surgery (Trauma, Emergent General Surgery, and Critical Care).
Jill L. Jakubus, PA-C, MHSA, MS is a physician assistant in the Department of Surgery at the University of Michigan providing care to the patients within the Division of Acute Care Surgery.
Ms. Jakubus received her BS degree in biomedical sciences and French from Western Michigan University in 2000. She completed her Master of Science degree in 2003 at Central Michigan University. From 2004 to 2008, she served as the data coordinator for the Michigan Trauma Quality Improvement Program at the University of Michigan. She completed the NSQIP surgical clinical reviewer training. Ms. Jakubus contributed to the formulation of the project since its inception with regard to creating trauma specific data definitions and optimizing data collection at the University of Michigan. She attained a Master of Health Services Administration from the University of Michigan in 2014.
As program manager, Ms. Jakubus ensures data integrity through data validation, coordinates analytic platforms and leads the development of the program’s IT infrastructure.
Dr. Yongqing Li, M.D. and Ph.D., is an Assistant Professor of Surgery in General Surgery. Dr. Li received his M.D. and M.S. in Pharmacology from China, before he acquired his PhD degree in Biochemistry and Molecular Biology from the University of Miami School of Medicine in 1995. He finished postdoctoral training first in the Department of Pathology at University of North Carolina, Chapel Hill in 1996 and later in the Dana-Farber Cancer Institute at Harvard Medical School from 1996 to 1998. Dr. Li was appointed as an Instructor of Medicine at Harvard Medical School in 1999, and led a group of scientists there from 1999 to 2003. He joined the Division of Trauma Surgery in Massachusetts General Hospital (MGH) at Harvard Medical School in 2005. In 2011, he was promoted to Assistant Professor of Surgery at Harvard Medical School, and worked as Director of the Trauma Surgery Research Laboratory at MGH before he was recruited to the University of Michigan in 2013. Dr. Li currently serves as Assistant Professor of Surgery and Director of the Trauma Translational and Clinical Research Laboratory at U-M.
Dr. Li started his academic career in cancer research in the 1990s. His research findings have been accepted in several prestigious journals such as Cancer Cell, Proc Natl Acad Sci U S A, Mol Cell Biol, Oncogene, J Biol Chem, etc., and are widely cited by research scientists. Knowing how to kill cancer cells has greatly helped him to protect normal cells from injury-induced apoptosis in his present trauma research. Since 2005, Dr. Li has focused his study on pharmacological treatment of traumatic hemorrhagic shock, traumatic brain injury, and sepsis with emphasis on histone modifying enzymes, including histone deacetylase (HDAC) and peptidylargine deiminase (PAD), as targets for therapeutics of trauma and sepsis. So far, he has published over 80 manuscripts and book chapters. Dr. Li has also discovered over 10 novel biomarkers which show potential for the early diagnosis and prognosis of hemorrhagic shock or sepsis. These inventions have been patented nationally and internationally, and are currently under validation in both pre-clinical and clinical studies.
Dr. Machado-Aranda is an Assistant Professor of Surgery in the Division of Acute Care Surgery at the University of Michigan. Originally from Caracas, he received his MD from Luis Razetti School of Medicine of Universidad Central de Venezuela, in 1998 achieving Magna Cum Laude honors and receiving the Dean's Medal and Award. Dr. Machado-Aranda completed his General Surgery residency at St. John Providence Hospital and Medical Centers in Southfield, MI. He previously completed a Postdoctoral Research Fellowship in Pulmonary and Critical Care Medicine at Northwestern University in Chicago, IL conducting basic science research in lung gene therapy and lung molecular biology. He has just finished his Surgical Critical Care Fellowship at University of Michigan in July 2011.
Dr. Machado-Aranda's clinical interests are in the areas of general surgery, trauma, acute care surgery, surgical critical care, lung contusion and ALI/ARDS. He is the recipient of the 2011 American Association for the Surgery of Trauma (AAST) Research and Education Foundation Scholarship Award to support his research in the areas of Gene Therapy for the acutely injured lung. He is currently studying the application of non-viral gene delivery, using electroporation mediated gene transfer in models of lung contusion.
Dr. Machado-Aranda is a member of the American College of Surgeons, the Society of Critical Care Medicine, the American Thoracic Society, the International College of Surgeons and the American Society for Gene Therapy. He is also an Advance Trauma Life Support (ATLS) instructor.
Dr. Machado-Aranda is fluent in Spanish and works as a mentor for the Latin American and Native American Medical Association (LANAMA). He is Board Certified in General Surgery and Surgical Critical Care.
Vahagn Nikolian is a Resident in the Department of General Surgery. Having completed his first 3 years of clinical training, Vahagn joined Hasan Alam's Trauma Translational Research Laboratory in 2015. Over the course of two years, Vahagn has performed a variety of experiments, ranging from in vitro studies, to large animal experiments, and clinical trials. His research focus has been dedicated to identification of logistically superior therapeutic strategies in the setting of traumatic brain injury in combination with extracerebral injury. Vahagn has been exceptionally productive during his research fellowship, authoring more than 20 peer reviewed articles and book chapters. Vahagn plans to complete his surgical training in 2019 and pursue a fellowship in colorectal surgery.
Dr. Park is Associate Professor of Surgery at the University of Michigan and Co-Director of the Surgical Intensive Care Unit at the University of Michigan Hospitals. She also currently serves as a member of the institutional Biorepository Governance Committee. She received her MD from Jefferson Medical College in 1982 and completed residency in General Surgery at the Thomas Jefferson University Hospitals in 1987. She completed an additional research fellowship investigating microvascular endothelial cell-vascular prosthetic interactions and worked with a team translating bench discoveries to preclinical and Phase I device studies in critical limb ischemia. She holds board certification in General Surgery and Surgical Critical Care and is a Fellow of the American College of Surgeons and the American College of Critical Care Medicine.
Dr. Park’s ongoing clinical and research interest is in the prevention and support of acute lung injury, particularly severe hypoxic respiratory failure in critically ill and injured patients. She serves as the Chair of the Ancillary Studies/Publication Committee for the USCIITG Lung Injury Prevention group, a national critical care research collaborative. She is the University of Michigan site principal investigator for two ongoing NIH/NHLBI-funded U01 trials (lung injury prevention and transpulmonary pressure-guided ventilation in early ARDS) and serves as a co-investigator for a third U01 trial with Pulmonary medicine. She has participated as a member of the steering committee of the original ARDSNetwork, the CIHR OSCILLATE investigator group, the American Association for Surgery of Trauma Multi Institutional Trials Committee and the Michigan Committee on Trauma. Her published work has focused on interventional and observational trials in lung injury prevention, ventilator strategies, extracorporeal support, trauma surgery and surgical critical care. She has presented nationally and internationally on lung injury prevention, extracorporeal support in severe influenza and advanced ventilator strategies. Dr. Park has been a recipient of the Society of Critical Care Medicine Presidential Citation and Annual Scientific Award.
Dr. Raghavendran is a trauma, critical care, and general surgeon. His primary research interests are lung contusion and aspiration-induced lung injury. He completed his medical education at Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) in Pondicherry, India. He then completed his surgery residency at Henry Ford Hospital in Detroit and his fellowship in Surgical Critical Care at Brown University in Providence, Rhode Island. He was an attending trauma surgeon at University at Buffalo, SUNY and was promoted to Associate Professor in July 2007. He moved to the University of Michigan in 2008.
Dr. Raghavendran has been funded by the National Institutes of Health (NIH) from 2006 and currently has an R0-1 award from NHLBI. His laboratory research focuses on studying the chemokine modulation in inflammatory mechanisms associated with lung contusion and its interaction with gastric aspiration. Additional areas of interest center on the role of Toll-like receptors and micro RNA in the pathogenesis of acute inflammatory response in direct forms of lung injury. The focuses of his clinical interests are with Surfactant replacement therapy, ARDS and Ventilator-associated pneumonia. He is as an associate faculty in Global reach at the medical school focusing on delivery of trauma care in India. He is currently the program director for the University of Michigan fellowship in surgical critical care and acute care surgery.
Dr. Rojas-Peña's research interests include cardiopulmonary pathophysiology, specifically cardiopulmonary mechanical support systems and extracorporeal life support systems that can be applied to cardiac arrest, extracorporeal support for multiple organ failure/end-stage diseases. His research expertise is in the development of large surgical models and bioengineering research projects to test novel extracorporeal support devices (pumps and oxygenators), bio-artificial organs, including the development of artificial lungs, artificial kidneys, artificial pancreas and the artificial placenta.
Dr. Rojas-Peña has worked to improve the techniques of extracorporeal support during cardiopulmonary resuscitation to improve survival outcomes minimizing neurological complications. In addition, he has worked in organ preconditioning and procurement with the aim of increasing the number of viable organs available for transplantation by using extracorporeal support to perfuse organs in-situ and/or ex-situ in animal models of donors after circulatory death (DCD). In addition, he has assisted in the transfer and use of large animal research models to numerous laboratories, U-M principal investigators, and private corporations that needed training in this area of research primarily to test devices prior to FDA studies or clinical use.
Dr. Wang is First Endowed Professor of Burn Surgery at the University of Michigan. He received his undergraduate education at Yale College and his MD at the University of Chicago Pritzker School of Medicine. He subsequently completed his surgical residency as well as a PhD in immunology at the University of Pittsburgh before joining the University of Michigan faculty in 1995. Dr. Wang serves as Director of the University of Michigan Burn Center as well as the State of Michigan Burn Coordinating Center. He is founding director of the multidisciplinary University of Michigan Program for Injury Research and Education (UMPIRE) as well as the International Center for Automotive Medicine (ICAM). For the past seventeen years, Dr. Wang has coordinated efforts to utilize the University of Michigan’s extensive medical resources in support of improved understanding of the mechanisms by which injuries are caused during motor vehicle crashes. Through collaborative case reviews, medical specialists, policy makers and engineers have jointly achieved a deeper understanding of the mechanisms of injury causation as well as potential ways to prevent such injuries from occurring. He has established the fellowship to train engineers in the interpretation of real life medical crash data and to facilitate the practical application of this data toward engineering improvements in vehicle safety design. He has also established several educational programs targeted toward rescue personnel and medical professionals to improve post-injury care.
Dr. Wang’s research is centered on injury. His basic science research focuses on local tissue responses to injury, burns and infection. His clinical research focuses on utilizing high throughput analysis of body composition characteristics (Analytic Morphomics) to assess patient fragility and frailty. Dr. Wang has been continuously funded by the NIH since 1990.
Nicole Werner, MD, MS is a general surgery resident and surgical critical care fellow at the University of Michigan. She has interests in cardiac resuscitative therapy, ex situ organ perfusion, and extracorporeal support; she is performing research within the ECLS laboratory around these interests. Dr. Werner also has a background in biomedical engineering, and has industry experience in designing implantable medical products and seeing them through the FDA approval process.
Aaron Williams is a Resident in the Department of General Surgery. Having completed his first 3 years of clinical training, Aaron joined Hasan Alam's Trauma Translational Research Laboratory in 2017. Over the course of his first year, Aaron has performed a variety of experiments, ranging from in vitro studies to large animal experiments. His research focus has been dedicated to identification of logistically superior therapeutic strategies in the setting of traumatic brain injury in combination with extracerebral injury. Aaron plans to complete his surgical training in 2021 and pursue a fellowship in cardiothoracic, transplant, or trauma surgery.