Each year the Grand Challenge targets a big problem and rewards bold solutions.


proposal and  to 'pitch' their idea to our expert panel made up of clinicians, business development and external partners. The best of the best then receive funding for their milestone-driven research over a 12-month timeframe.

The Grand Challenge  begins with a 'state of the art' discussion, followed by the release of a Request for Proposal. This two-part process begins with the submission of two-page proposals. We then invite the most promising teams to submit a detailed 10-page


It is often the minutes and hours following a traumatic brain injury (TBI) that can determine whether a patient lives or dies. There has been little advancement in developing diagnostic tools and treatments, which is why we partnered with the Joyce and Don Massey Family Foundation to fund innovative solutions that could improve outcomes after severe TBI.


Sepsis or 'blood poisoning' occurs when the body's natural response to infection becomes unbalanced, runs out of control and leads to multiple organ damage. Difficult to diagnose, and even harder to treat, sepsis claims more lives than any cancer. Our researchers were challenged to undertake the difficult task of finding new ways to address the current sepsis treatment gaps.