Sepsis and Multi-Organ Failure — Latest News — The Max Harry Weil Institute for Critical Care Research and Innovation

Weil Institute K12 scholar awarded over $500,000 to study how cholesterol affects sepsis immune response

Initial research finds inhibiting cholesterol production protects against sepsis toxicity.

U-M Team Receives NIH Grant for Collaborative Research to Speed ARDS Diagnosis

University of Michigan researchers examine if molecular compounds in exhaled breath could lead to improved diagnosis and tracking of acute respiratory distress syndrome (ARDS).

Four Midwest centers unite to advance novel therapeutics

Weil Institute members form regional consortium to study critical illness syndromes and empower future research efforts.

Newsweek highlights gut microbiome study led by Weil Institute Deputy Director

Dr. Robert Dickson and his team found that, in patients with sepsis, body temperature was directly linked to the variety of species in their gut microbiome. Some species make the patients more effective at increasing their body temperature.

SepsisKate MurphyFebruary 2, 2023Sepsis and Multi-Organ Failure, Bacteria, Robert Dickson

Study led by Weil Institute Deputy Director reveals gut microbiome's role in regulating body temperature

Led by Robert Dickson, MD, a team of Weil Institute and Michigan Medicine researchers examined the interplay between gut bacteria, temperature fluctuation, and health outcomes

SepsisKate MurphyJanuary 24, 2023Sepsis and Multi-Organ Failure, Robert Dickson, Bacteria

Frankel Innovation Initiative awards Weil Institute investigators $250,000 to identify sepsis-causing bacteria faster and more accurately than gold-standard methods

A research team from the Weil Institute and Michigan Medicine received $250,000 to support work on a new tool that could revolutionize pathogen detection in patients with sepsis.

SepsisKate MurphyJanuary 13, 2023Sepsis and Multi-Organ Failure, Award Announcement, Scott VanEpps

Anti-anaerobic antibiotics associated with increased risk of mortality in critically ill patients

A common clinical practice may be inadvertently harming patients, according to new research published in the European Respiratory Journal. The team of Weil Institute and Michigan Medicine researchers behind the study suggest that administration of antibiotics with activity against anaerobic bacteria has a profound effect on the gut microbiome and, ultimately, an adverse impact on critically ill patients.

SepsisKate MurphyOctober 13, 2022Sepsis and Multi-Organ Failure, Robert Dickson, Press Release

Weil Institute Researchers Developing New Methods of Managing Pediatric Sepsis

A new study integrating biomolecular immune response data, machine learning and rapid pathogen detection could pave the way for improved methods of diagnosing and treating sepsis in developing immune systems.